If I may step away from ethical palaeontology for a moment...
For years and years my mother's family have been convinced there is a genetic link to left-handedness. Maybe peer-reviewed research had been published on the subject, but it never made it into the British Medical Journal, which nearly everyone in the family have all read at some point.
Grandpa was left-handed. One of his grandparents was left-handed too (I forget which one, although it may have been his maternal grandmother - that sounds right). None of his children were left-handed, although my mother and my aunt both have one left-handed child: my cousin and me. The fact that left-handedness had skipped a generation on two occasions rendered chance an unlikely explanation, and, considering Grannie and Grandpa and their descendants, three southpaws in a family of 12 is way over the statistical norm of 10%.
I was delighted to see the BBC report Gene for left-handedness is found today. Sadly, I don't have full-text access to Molecular Psychiatry, but I've had a look at the abstract. And the first thing that leapt out of the title was: "LRRTM1 on chromosome 2p12 is a maternally suppressed gene that is associated paternally with handedness and schizophrenia". The abstract then goes on to mention "maternal downregulation". I feel completely out of my depth here - I last did genetics in detail in A-level biology (although we discussed Hox, Pax and Sonic Hedgehog genes in Vertebrate Structure and Palaeobiology classes). But does this correlate with the fact that the mothers of the left-handed members of the family (Grandpa, my cousin and me) did not or do not show left-handedness? Does the suppressed gene nevertheless manifest itself in the creative, artistic, musical minds of my mother and aunt? I'm sure a geneticist would love our family as a case-study. It's a pity the research has only just come out now as Grandpa would have been fascinated by it.
Left-handed people are traditionally supposed to be more creative, although a quick trawl through the related articles shows that in addition to this Left-handers "think" more quickly, Left-handers "better in fights" and Left-handed people "don't die young" (very reassuring). And we're apparently excellent at cricket and being cavemen. Although one wonders if the cave paintings were just carried out by the creatively-minded lefties of the tribe while the right-handers were off doing more useful stuff like hunting and gathering.
I should point out, however, that there is absolutely no history of mental illness in our family - we've done quite well out of that one. We'll all need pacemakers (I always called Grannie the Duracell Bunny because she ran on batteries), and we'll have appalling arthritis, but that's it.
The authors allude in the abstract to the gene's role in "cognitive and behavioural evolution". I'd love to know the "reason" for left-handedness. I understand handedness exists in other animals. I suppose a mutation, if it does not confer an advantage or disadvantage on the organism, will remain in the population at a constant (perhaps slightly increasing?) percentage. Maybe we're all just the result of random, harmless mutations, condemned to spend our days smudging our fountain pen script, unable to use cake forks or scissors, drinking from the wrong side of the slogan mug, swapping over the mouse buttons, needing our own rulers and having incredible hassle at public transport ticket barriers.
For years and years my mother's family have been convinced there is a genetic link to left-handedness. Maybe peer-reviewed research had been published on the subject, but it never made it into the British Medical Journal, which nearly everyone in the family have all read at some point.
Grandpa was left-handed. One of his grandparents was left-handed too (I forget which one, although it may have been his maternal grandmother - that sounds right). None of his children were left-handed, although my mother and my aunt both have one left-handed child: my cousin and me. The fact that left-handedness had skipped a generation on two occasions rendered chance an unlikely explanation, and, considering Grannie and Grandpa and their descendants, three southpaws in a family of 12 is way over the statistical norm of 10%.
I was delighted to see the BBC report Gene for left-handedness is found today. Sadly, I don't have full-text access to Molecular Psychiatry, but I've had a look at the abstract. And the first thing that leapt out of the title was: "LRRTM1 on chromosome 2p12 is a maternally suppressed gene that is associated paternally with handedness and schizophrenia". The abstract then goes on to mention "maternal downregulation". I feel completely out of my depth here - I last did genetics in detail in A-level biology (although we discussed Hox, Pax and Sonic Hedgehog genes in Vertebrate Structure and Palaeobiology classes). But does this correlate with the fact that the mothers of the left-handed members of the family (Grandpa, my cousin and me) did not or do not show left-handedness? Does the suppressed gene nevertheless manifest itself in the creative, artistic, musical minds of my mother and aunt? I'm sure a geneticist would love our family as a case-study. It's a pity the research has only just come out now as Grandpa would have been fascinated by it.
Left-handed people are traditionally supposed to be more creative, although a quick trawl through the related articles shows that in addition to this Left-handers "think" more quickly, Left-handers "better in fights" and Left-handed people "don't die young" (very reassuring). And we're apparently excellent at cricket and being cavemen. Although one wonders if the cave paintings were just carried out by the creatively-minded lefties of the tribe while the right-handers were off doing more useful stuff like hunting and gathering.
I should point out, however, that there is absolutely no history of mental illness in our family - we've done quite well out of that one. We'll all need pacemakers (I always called Grannie the Duracell Bunny because she ran on batteries), and we'll have appalling arthritis, but that's it.
The authors allude in the abstract to the gene's role in "cognitive and behavioural evolution". I'd love to know the "reason" for left-handedness. I understand handedness exists in other animals. I suppose a mutation, if it does not confer an advantage or disadvantage on the organism, will remain in the population at a constant (perhaps slightly increasing?) percentage. Maybe we're all just the result of random, harmless mutations, condemned to spend our days smudging our fountain pen script, unable to use cake forks or scissors, drinking from the wrong side of the slogan mug, swapping over the mouse buttons, needing our own rulers and having incredible hassle at public transport ticket barriers.


